Primo Depot: Benefits, Results, Stacking and What To Expect

Primobolan is an oral or injectable anabolic androgenic steroid (AAS). Primo is often referred to as Methenolone enanthate or just Primo. Because it does not have estrogenic effects, has minimal side effects, and helps bodybuilders develop lean muscle mass, it is utilized by bodybuilders. Primo has a reputation for being a weak steroid, which is somewhat justifiable. You will not establish new lifting records or gain a lot of weight while on this steroid, but you will create great bulk over the course of many weeks.

Despite being one of the most costly steroids on the market, many individuals in the bodybuilding community don’t fully understand this steroid. Primobolan is likely to be appreciated by those who have established a firm foundation via years of training. It is a generally innocuous chemical that does not cause sleep disturbances, blood pressure symptoms, or gynecomastia dangers.

What is Primo Depot?

Primobolan Depot is the injectable form of methenolone derivative. Primobolan oral has the same component as methenolone acetate. In primo depot, an enanthate ester is employed to modulate the rate of steroid release from the injection site.

Methenolone enanthate has a similar pattern of steroid release to that of testosterone enanthate, where hormone levels in the blood stay considerably elevated for around two weeks.

Methenolone by itself is a steroid with somewhat significant anabolic effects and little androgenic action. Comparatively to Deca-Durabolin (nandrolone decanoate), its anabolic effects are slightly less.

The usage of methenolone enanthate is particularly frequent during cutting cycles, when the primary goal is not to increase raw mass but rather to increase lean mass.


History of Primobolan

Primobolan’s basic composition was made public for the first time in 1960, and the pharmaceutical firm Squibb began producing the first “usable” version of the medicine for the American market in 1962. This initial formulation was methenolone enanthate, marketed at the time as “Nibal depot.”

In the second part of the same year, the oral acetate formulation was launched and marketed under the brand name “Nibal.” Due to Schering’s rapid purchase of all rights to the methenolone hormone in the mid-1960s, manufacturing runs for both of these medicines were severely limited.

It was at this time that its commercial name, formerly Nibal, was changed to Primobolan for the oral formulation and Primobolan Depot for the injectable formulation. Since then, these names have been extensively utilized.

Schering advertised Primo as its flagship steroid after acquiring the rights to do so. Schering emphasized the product’s favorable risk-to-benefit ratio when it came to retaining lean tissue and guaranteed that it became a national exclusive.

Due to its exclusivity, it was taken off the market in the United States. Since then, it has never made an official reappearance. In the United States, the substance is still FDA-approved for human usage, which is an unusual fact.

U.S. medical experts continued to place special orders for Primobolan for medicinal usage after the drug was removed off the market. This is owing to the fact that it was regarded as remarkable in terms of lean tissue nutrition.

It was supplied to patients in the 1960s as a therapy for disorders that caused muscular atrophy largely because to its benefit.

It continued to enjoy great popularity throughout the 1960s for the aforementioned reasons, and it didn’t take long for the bodybuilding community to recognize its positive benefits.

At the time, this led to its incorporation into both cutting and bulking cycles.

The product had its most comprehensive advertising effort as a result of its assimilation into the bodybuilding culture, particularly when the 1970s rolled around and its popularity grew. Primobolan is reportedly one of Arnold Schwarzenegger’s favorite anabolic steroids.


What is in Primobolan?

Dihydrotestosterone (DHT) is a structurally modified version of the derivative methylone. The hormone is composed of DHT with two extra double bonds at the first and second carbon atoms.

This dramatically increases the anabolic characteristics of the steroid. In addition, it has a 1-methyl group that protects the liver from degrading the hormone. Primobolan Depot includes methenolone with a linked enanthate ester.

This ester is introduced to modulate the hormone’s release timing and drastically slow it down. Important information: injectable Methenolone acetate formerly existed. However, this product was discontinued in 1993.

Injectable Methenolone Acetate is a somewhat rare substance. Primobolan Depot is the only injectable type of Methenolone that the majority of individuals will have access to if they want to use this hormone.

Primobolan depot is a moderate anabolic steroid with an androgenic rating of 44–57 and an anabolic value of 88. Examine the rating system to see whether these ratings have teeth. The amount of the hormone testosterone serves as the standard for all evaluations.

The value of testosterone in both groups is 100. Methenolone has a lower anabolic grade, which, although not being wildly inaccurate, might be deceptive. The rating does not adequately reflect the amount of lean tissue growth attributes provided by Primobolan Depot.

Primobolan Depot possesses a variety of features often associated with anabolic steroids, including its direct-acting nature. The hormone has the ability to stimulate protein synthesis, increase red blood cell creation, and inhibit glucocorticoid hormone production.

These features may not be as prominent in Primobolan Depot as they are in many other anabolic steroids, but they do add to its anabolic steroid usefulness.

This steroid shines because to its ability to promote nitrogen retention in muscles and its high affinity for the androgen receptor. Given that nitrogen constitutes around 16% of all muscle tissue, the enhanced nitrogen retention is considerable. Low nitrogen levels induce a catabolic condition, but the more nitrogen we can keep, the more anabolic we can remain. The binding of androgen receptors is the subsequent key element, since it has been linked to lipolysis.

Despite the fact that practically all anabolic steroids operate to enhance metabolic strength and power, the strong binding affinity for the androgen receptor actually promotes fast fat loss. Due to its enhanced nitrogen retention and above-average nitrogen retention, Primobolan Depot is an exceptional cutting steroid.

Methenolone has been shown to be beneficial to the immune system. Primobolan Depot has proven to be highly beneficial in the treatment of AIDS-related immunological issues and muscle atrophy.

It is likely that additional steroidal agents are employed in these cases. It is unlikely to be the only prescription, as it will not promote major bulk features. In these conditions, however, its mild anabolic qualities and immunological enhancement make it an excellent choice.

Regular steroid users may find Primobolan Depot’s ability to boost the immune system to be of significant use. If your immune system is stronger, your health will improve and it will be simpler to achieve your objectives.

However, it can be quite beneficial during a cutting cycle, as immune systems typically decrease slightly when on a tight diet. This is particularly true for professional bodybuilders, who regularly undertake diets that would take the average person a week to finish.

Primo Oral Vs Primo Depot

Intravenous use of Primobolan offers several benefits versus oral administration. The liver will metabolize a considerable amount of the active component, which is the major reason why oral primo does not generate exceptionally strong results. Because the oral formulation is weaker, the doses must be greatly increased, which might be costly for some clients. Therefore, we always recommend injectable primo for the most effective and cost-efficient effects.

Benefits of Primo Depot For Bodybuilding

Primobolan Depot is not the best choice for the majority of individuals seeking a bulking steroid to utilize during the off-season. The steroid is just unsuitable for lean muscle mass increase. Due to the absence of estrogenic action in this steroid, its administration does not result in fluid retention. Therefore, any weight acquired as a result of usage will consist solely of lean muscle mass, despite the fact that the quantity of weight gained may not be large.

During the off-season, however, girls are exempt from this rule. Women are far more susceptible to the chemical, and it may provide the off-season anabolic boost necessary for development. Primobolan is recognized as one of the most efficient anabolic steroids for female athletes to utilize during the off-season.

Keep in mind that the overall bulk will depend mostly on the individual’s diet and total dose. The majority of women do not gain more than 30 pounds, which is reassuring to individuals who are anxious about acquiring excessive mass. You may regulate the amount of muscle mass you gain by keeping a healthy diet and taking the supplement in moderation.

You will be able to gain muscle over the offseason with minimal fat buildup. You will get this benefit as a result of utilizing this steroid.

Now is the perfect time for both men and women to utilize Primobolan Depot.

This steroid is exceptional for retaining muscular tissue. In order to decrease the amount of fat deposited in our bodies, we must burn more calories than we consume. Even if you consume the healthiest diet in the world and exercise until you pass out, you will not lower the amount of fat stored in your body if you do not burn more calories than you consume.

As a result of caloric restriction, some lean muscle mass will be lost. Due to the deficit, the body will be forced to obtain the energy it needs from wherever it can find it. In an effort to preserve body fat, the body will be tempted to extract energy from muscle tissue despite the fact that the objective is to pull energy from fat. This is the function of the human body.

Using Primobolan Depot as a dietary supplement will allow you to keep muscle mass while lowering total body fat. Additionally, it will ensure that the pace at which body fat is burnt is greatly accelerated. Those who use Primobolan Depot throughout the cutting phase also report that, as their body fat percentage decreases, their muscles become substantially more defined.

Primobolan Depot is an additional steroid that boosts athletic performance. It is capable of producing strength improvements and has a positive impact on both muscle endurance and recuperation. Additionally, it has the ability to promote muscular growth.

In a similar line, the fact that it is not a significant bulk builder makes it an ideal option for many athletes. A number of sportsmen do not wish to gain significant bulk. Sometimes, adding bulk might be harmful to performance. The most important thing an athlete can do to protect himself from inquisitive and suspicious eyes is to avoid rapid gains in muscle bulk.

Risks and Side Effects

Primobolan Depot has the potential for undesirable side effects, yet it is one of the safest anabolic steroids that an adult might consume. The probable negative effects of Primobolan Depot will be far less severe than those of other anabolic steroids. Although there may still be negative effects, we will find that they are often far less severe than those of most anabolic steroids. In reality, it is quite probable that using this steroid as a supplement would not result in adverse consequences. We have categorized the side effects of Primobolan Depot and supplied you with all the necessary information to understand them.


There are no estrogenic side effects associated with Primobolan Depot. This anabolic steroid does not aromatize and lacks progestin characteristics. Due to this, using Primobolan Depot prevents gynecomastia and fluid retention. Additionally, it reduces the likelihood of developing blood pressure issues. Significant water retention is typically associated with high blood pressure, which Primobolan Depot also prevents.


Even though Primobolan Depot is a moderately anabolic steroid, it may cause androgenic side effects. Acne, fast male pattern baldness, hair loss, and body hair development are possible adverse effects. Few users of this steroid will have acne-related complications. There are exceptions, with acne-sensitive individuals comprising the most frequent exception. In terms of hair loss, this might be one of the most dangerous steroid products on the market. Those who are not genetically predisposed to male pattern baldness are not at danger, while those who are will likely experience accelerated thinning.

Commonly, 5-alpha reductase inhibitors are used to address the androgenic side effects of anabolic steroids. The most widely used formulation of finasteride inhibits the 5-alpha reductase enzyme. This enzyme is responsible for converting testosterone to DHT. Primobolan Depot already includes DHT, therefore any possible inhibitory effects will be minor because the hormone is not broken down by 5-alpha reductase.

Primobolan is a moderate anabolic steroid with androgenic characteristics that may cause virilization in females. The growth of body hair, a deepening of the voice cords, and clitoral enlargement are all indicators of virilization. Such effects are very dependent on the total dosage and individual sensitivity to the methenolone hormone. Most individuals who supplement in low to moderate doses will not suffer adverse effects. You are strongly urged to discontinue use of the drug immediately if virilization symptoms arise for any reason. If you quit using at the first hint of withdrawal symptoms, you will observe that they swiftly disappear. If usage continued and symptoms are ignored, there is a high likelihood that the consequences will become permanent.


Primobolan Depot should not substantially influence blood pressure. It is possible to have high blood pressure, particularly if an underlying condition already exists, although it is typically unlikely. Primobolan Depot’s cholesterol-related adverse effects will be the most obvious in terms of cardiovascular side effects. Although it should be far less than the majority of oral steroids, this steroid might have a more significant negative effect on cholesterol than testosterone. Nevertheless, there is unquestionably a danger, which may result in a decrease in HDL cholesterol (the good cholesterol) and a rise in LDL cholesterol (bad cholesterol).

Due to Primobolan Depot’s possible cholesterol-harming effects, a cholesterol-friendly lifestyle will be essential. This will need consuming a diet that is low in saturated fats and simple carbohydrates, high in omega fatty acids, and cholesterol-friendly. It is also recommended to perform a great deal of cardiovascular activity. Everyone is strongly encouraged to check their cholesterol levels in all circumstances.


Each anabolic steroid inhibits the synthesis of natural testosterone, however the degree of inhibition varies considerably amongst drugs. Compared to other anabolic steroidal hormones, methenolone’s suppressive impact is much less. Trenbolone, Nandrolone, and Testosterone all suppress much more than Methenolone. Primobolan Depot must be used with exogenous testosterone, despite the fact that the suppression is substantially milder than with the medicines listed above. A lack of exogenous testosterone treatment will result in low testosterone levels in men. This truth cannot be altered by your DNA or the myths you’ve heard. Exogenous testosterone will substantially enhance the experience of its users. People who don’t risk having several signs of low testosterone. These symptoms are usually exceedingly harmful, incredibly bothersome, and detrimental to one’s quality of life. Women who use Primobolan Depot will not require testosterone replacement therapy.

Once Primobolan Depot and all anabolic steroids are discontinued, the body will produce testosterone naturally. In fact, this is one of the steroid classes from which recovery is the simplest. Post-Cycle Therapy (PCT) is still strongly recommended for the vast majority of individuals. A PCT program will reduce your total recovery time and improve your health. Although this technique will not immediately restore normal testosterone levels, it can greatly decrease the recovery time. More importantly, it will ensure that you have sufficient testosterone for good bodily function as your testosterone levels steadily rise.

It is essential to note that this is based on the assumption that there has never been a case of low testosterone before. It also assumes that improper steroid supplementation practices have not caused considerable injury to the Hypothalamic-Pituitary-Testicular-Axis (HPTA).


Primobolan Depot is not hepatotoxic, therefore it will not stress or injure the liver.


Dosage and Administration Recommendations

The average weekly dose of Primobolan Depot for men is between 100 and 200 mg. After a few weeks, the initial dosage is often reduced from 200mg per week to 100mg per week. In certain instances, the dosage may be lowered by up to 100 mg every two weeks.

300 mg per week is considered the minimum dosage for male athletes. During a cutting phase, 200 mg per week will provide catabolic protection, but 300 mg per week will be significantly more effective. The majority of men may easily handle 400–500 mg per week of this rather moderate anabolic steroid.

Even 600 mg per week should be well within the area of control for the majority of guys. Although weekly dosages of 600 mg or more are common, it is crucial to remember that large levels may exacerbate the steroid’s androgenic effects.

Typically, 8–12 weeks of continuous usage is recommended. Primobolan Depot combines well with the overwhelming majority of anabolic steroids. Since it will be taken most frequently during the cutting phase, anabolic steroids like Anavar, Masteron, Trenbolone, and Winstrol are usually supplemented.

Schering has never openly declared the normal Primobolan Depot dosages, despite the drug’s usage in women. The average female athlete requires between 50 and 100 mg of Primobolan Depot weekly. With such a dose range, the majority of women should be able to control the degree of virilization.

Remember that individual sensitivity varies, and while some people may have virilization symptoms at this dose level, the vast majority will not. Women who take more than 100 mg will almost probably suffer virilization symptoms. This is practically guaranteed if it is coupled with other steroids.

4-6 weeks of usage, regardless of the overall dose, is often sufficient for the majority of women. Given that Methenolone only comprises 4 weeks of an 8-week cycle, Anavar and Primobolan Depot stacks are helpful for many women. Regarding female use, many women may find oral contraceptives appealing.

How it Compares to Other AAS

Primobolan Depot is a popular anabolic steroid for several reasons, including those listed below: There is no need for concern regarding estrogenic side effects to start. Therefore, it is a fantastic option for both men and women who are sensitive to the hormone.

Second, unlike other anabolic steroids such as Anadrol, it does not produce hepatotoxicity (liver damage), allowing you to utilize it for extended periods of time without endangering your liver. Finally, there is low aromatization and water retention with Primo, so there is no need to worry about becoming bloated or retaining excessive water weight. This also eliminates the need for an anti-estrogen throughout your period!

Primobolan Depot is an excellent steroid choice for those who wish to grow without experiencing the regular adverse effects of steroids. Stacking refers to the practice of combining Primobolan Depot with other anabolic steroids, such as Testosterone Cypionate, Equipoise, Deca Durabolin, and Anavar for men, as well as Winstrol (if increasing strength and/or athletic performance is the primary aim).

Primo is beneficial for women throughout the bulking periods of their training, which demand them to ingest more calories than usual. Trenbolone is another wonderful choice, however women do not always handle it well. How do its effects compare to those of human growth hormone (HGH)? Primobolan Depot outperforms HGH in every conceivable way.

During the bulking phase, it is usually used with HGH in the same manner that many anabolic steroids are to promote fast muscle building while also supporting the athlete in keeping lean tissue.

However, bear in mind that you should not take Primo in conjunction with any anabolic steroid. Doing so is a guaranteed way to attract difficulty, and excessive stacking may have catastrophic consequences.

Can Women Use Primobolan Depot?

Primobolan Depot use by females is fully safe. Primobolan does not aromatize and does not produce many of the feminizing side effects that testosterone can cause, such as hair growth. For cutting cycles, this compound stacks well with trenbolone and testosterone.

During contest preparation, some female bodybuilders contemplate stacking Primo and Winstrol to “lean out” while avoiding the masculinizing side effects of harsher steroids such as Equipoise or Anadrol. This is done to attain their objectives of lowering body fat while retaining muscle mass.

In addition, it is a great steroid to stack with Masteron if you are a lady who needs to slim down without losing mass. Masteron is minimally anabolic and low in androgenic activity, therefore it will not have a significant detrimental effect on muscle tissue. Stacking this steroid with Deca-Durabolin will accelerate your progress toward your goals.

Even if anabolic steroids such as Trenbolone and Masteron are not the major cause of gynecomastia (the development of female breast tissue) or water retention, you will still need to be cautious if you mix Primo with them. This is due to the fact that anabolic steroid medications such as Trenbolone and Masteron are not the major cause of these negative effects.


Final Thoughts

Primobolan Depot is a moderate anabolic steroid that has been well-liked by athletes for decades due to its low androgenic properties, low adverse effect profile, and ability to provide good results even at extremely low dosages. These factors contribute to the popularity of Primobolan Depot. It may be taken as part of a bulking stack or reducing cycle, depending on the individual’s goals, or it can be used as a beginner-level steroid by athletes competing in smaller weight classes. Regardless of how it is used, there are a few points to bear in mind:

Be mindful of your overall dose; the most common error made by novice steroid users is combining short ester bases and long ester bases in a single stack.

Remember that Primobolan Depot is typically the “weakest” ingredient used when stacking multiple compounds from different families, so take this into mind when determining your total dose.

It is vital to monitor the duration of Primobolan Depot use because, in most situations, it should not be used for extended periods of time.

It is time to discontinue the use of Primobolan Depot or any other anabolic steroid when your body’s natural testosterone production begins to decrease after a course of therapy. This applies to all anabolic steroids.

In this case, it may be prudent to consider taking prophylactic measures, such as clomid or nolvadex, in order to minimize the possible harm that might be caused by high estrogen levels.

12 Comments to “Primo Depot: Benefits, Results, Stacking and What To Expect”

  1. I’ve been using Primobolan Depot for over a year. It helps me maintain a steady, natural build and is great to use as a “bridge” toward my next cycle. The first time I used it, I was able to pack on 20 pounds of muscle without adding any fat. It’s one of the best things that I have found on the market at such an affordable price! Also, the benefits of Primo Depot for bodybuilding have been proven by research. I will be using this product for a long time!

  2. Taking 600+ mg Primobolan depot dosages gave me a significant increase in strength. But I was absolutely losing A LOT of weight! So I cut back to 300mg, and the symptoms were greatly reduced. Primobolan depot stacks well with Dianabol, Anadrol, and Winstrol. You will notice a significant reduction in body fat and water retention when you stack Primobolan depot with these drugs.

  3. I started using Primobolan Depot stacks about a year ago and I’ve seen fantastic results with it. I was able to gain muscle and strength. I was able to put on 5 lbs in the first month! I didn’t even have to go crazy with my diet, but it’s always good to eat clean while you are stacking Primobolan Depot with anything else. The best Primobolan Depot dosages that I have found is 100 mg ED and a week later, another 100 mg ED. That’s 400 mg of Primo a week. It’s not too much at all and it gives great results!

  4. Primobolan Depot is the single best anabolic steroid on the market. I’ve been using dose of Primobolan Depot for a couple of years now and I never get less than the muscle mass and definition that I desire. It’s also a lot more affordable than other products, but you still get all of the benefits…definitely my go-to drug!

  5. I just started back on a Primobolan cycle after being off for four or more years, being homeless, and being addicted to heroin. I’ve been clean for nine months, and I’m currently running tests at 800mg per week. However, I’m going to add 700mg dose of Primobolan Depot per week, as well as hgh for the first time, and I can’t wait!

  6. Primobolan, an injectable form of methenolone has always been a favorite of mine. I used to take it in ampules, I believe. Wonderfully clean product. I loved using it with test propionate, sustanon 250, EQ, Deca, and Anavar. yes! Although it took some time to work, what a product! The use of Primobolan was always very effective in my case, I recommend it.

  7. I’ve been using Primobolan Depot or the injectable form of methenolone for the last six months and I am absolutely in love with it. The pump I get from it is out of this world, better than any other steroid that I’ve ever used. After every cycle of use of Primobolan, my bodybuilding physique looks as though it’s never lost any muscle mass and everyone remarks about how I’m still looking as ripped as when I first started. It has helped me maintain a level of leanness and muscle mass that is truly amazing.

  8. I currently take 600 mg of Primobolan oral along with 325 mg of Testosterone Cypionate and 100 mg of Anavar, and I ADORE the use of Primobolan. I truly see the difference in my muscle mass and strength. Primo has helped me maintain my muscle mass while on TRT, and at the same time has allowed me to drop down from 250 mg of Test per week to 200 mg of Test per week.

  9. Man, I am on Primo Depot, And I was completely different. I completed the 300 test with the 300 Decca and was at my most horny ever. Primobolan is the best steriod for me.

  10. I’ve been taking Primobolan Depot for a few months now and I’m really happy with the results. The popularity of Primobolan Depot is growing and it’s becoming a very popular androgen. More steroid users are beginning to use Primobolan Depot because it’s not as harsh on the body as many of the stronger anabolic steroids and doesn’t have as strong of side effects. The duration of Primobolan Depot is also longer than many of the other anabolic steroids. This makes Primobolan Depot a very popular choice for many people.

  11. I’m so happy I found Primobolan Depot! I’ve been stuck on the same weight for months and I finally made my breakthrough with Methenolone. It’s perfect for cutting, bulking or just maintaining muscle mass. The only downside is that it isn’t safe to use in a show prep cycle because of the high level of water retention.

  12. As I aim to get leaner, I’m running 600 mg of Primo and 400 mg of Test. The benefits of Primo depot for bodybuilding are awesome! I’m looking forward to using Primobolan Depot more in the future.

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